Analytical

Save Time and Money through Accurate Analysis

Advanced analytical characterization provided by Dowpharma^SM is based on The Dow Chemical Company’s long history as a leader in the analysis of polymers.

This advanced analytical characterization allows you to:

• Reduce cost of goods for your conjugation via increased batch-to-batch consistency
• Meet the specifications of your PEG conjugate
• Make more informed manufacturing decisions

Add Certainty with Dowpharma Analytical Capabilities
Dowpharma’s powerful analytical capabilities help you understand how the activated PEG is performing in your system.

The starting material for activated PEGs is mPEG-OH. The mPEG-OH contains small amounts of PEG diol. When the mPEG-OH is activated for conjugation, several PEGs can be formed:

• The desired activated mPEG-X
• Di-activated PEG that comes from PEG diol
• Any mPEG-OH that has not been activated

It is important to understand the concentration of these various PEGs as they have a direct impact on the quality of your conjugate. 

The industry typically utilizes NMR to determine functionality, but this technique does not allow measurement of the various PEGs. Our advanced analytical techniques allow us to separate and quantify the various PEGs. This is illustrated by the different elusion times in the LC of each of these PEGs as shown in the accompanying chart.

These capabilities are only available at Dowpharma.

Find out more about ordering PEGs from Dowpharma. Or, if you have questions, contact us.

^SMService mark of The Dow Chemical Company