Chemistry

Activated PEG Chemistry
Activated PEGs are poly(ethylene) glycols which typically have one end capped as a methyl ether and the other end activated for conjugation with a biopharmaceutical.

Conjugation Chemistry – What is the Right Activated PEG for You?

The NHS ester has been widely used for many years. However, propionaldehyde and p-nitro phenyl carbonate offer a viable solution for conjugation with amines.

At Dowpharma^SM, all our activated PEGs, regardless of molecular weight, have narrow polydispersity and low levels of di-activated PEG. They are also characterized by our advanced analytical capabilities that:

• Reduce cost of goods for your conjugation via increased batch-to-batch consistency
• Meet the specifications of your PEG conjugate
• Allow you to make more informed manufacturing decisions

Find out more about ordering PEGs from Dowpharma. Or, if you have questions, contact us.

^SMService mark of The Dow Chemical Company