Small Molecules

Trost Allylic Alkylation

Brochures, Flyers and Other Literature
pdf icon Trost Molybdenum Technology exclusive license from Stanford Univ. (109 KB PDF)
pdf icon Trost Palladium Technology Exclusive license from Stanford Univ. (111 KB PDF)
pdf icon Application of Trost palladium catalyzed asymmetric allylic alkylation technology (313 KB PDF)

Dowpharma Scientific Publications
Please find detailed a synopsis of the papers and publications on Trost Allylic Alkylation that scientists from DowpharmaSM have published and contributed to since 1998. Due to copyright law we are unable to reproduce the papers online. As such we have quoted the publication reference.

Catalytic Asymmetric Synthesis of Ethyl (1R,2S)-Dehydrocoronamate. 
Fox, M. E.; Lennon, I. C.; Farina, V.  Tetrahedron Letters, 2007, 48, 945-948.

A Convenient and Scaleable Synthesis of 11,12-Diamino-9,10-ethanoanthracene and Its Enantiomers.
Fox, M. E.; Gerlach, A.; Lennon, I. C.; Meek, G.; Praquin, C. Synthesis, 2005, 3196-3198.

Optically Active 3,4-diazaphopholane Ligands and Their Application in Asymmetric Hydroformylation and Allylic Alkylation Reactions (perspective).
Landis, C. R.; Rand, C. L.; Klosin, J. Chimica Oggi; Chemistry Today. Chiral Technologies Today supplement, 2005, pages 12-16.

Applications of the Trost Palladium(0) Catalyzed Asymmetric Allylic Alkylation Technology.
Lennon, I. C. Chimica Oggi; Chemistry Today. Chiral Catalysis – C-C Coupling and Oxidation supplement, 2004, pages 11-14.

An Efficient, Palladium-catalyzed, Enantioselective Synthesis of (2R)-3-butene-1,2-diol and its Use in Highly Selective Heck Reactions.
Cheeseman, N.; Fox, M.; Jackson, M.; Lennon, I. C.; Meek, G. Proc. Natl. Acad. Sci. USA. 2004, 101, 5396-5397.

(R,R)-1,2-Bis(aminocarbonylphenyl-2’-diphenylphosphino)cyclohexane.
Lennon, I.C. In Handbook of Reagents for Organic Synthesis. Chiral Reagents for Asymmetric Synthesis, Paquette, L.A. (ed). John Wiley & Sons Ltd. 2003, page 99.

A Novel Synthesis of 5-hydroxy-2,2-dimethyl-10-propyl-2H-pyrano[2,3-f]chromen-8-one.
Fox, M. E.; Lennon, I. C.; Meek, G. Tetrahedron Lett. 2002, 43, 2899.

Speeding up Synthesis of Chiral Chemicals.
Lennon, I. C. Chemical Engineering 2001,108, 70.

A Novel Asymmetric Route to 2-amino-1,2,3,4-tetrahydronaphthalenes.
Harris, M. C. J.; Jackson, M.; Lennon, I. C.; Ramsden, J. A.; Samuel, H. Tetrahedron Lett. 2000, 41, 3187.

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